Deep Learning-Based Prediction of Gastric Cancer Response to Neoadjuvant Chemotherapy

Status: Recruiting
Location: See all (22) locations...
Intervention Type: Drug
Study Type: Observational
SUMMARY

This study seeks to develop a deep-learning-based intelligent predictive model for the efficacy of neoadjuvant chemotherapy in gastric cancer patients. By utilizing the patients' CT imaging data, biopsy pathology images, and clinical information, the intelligent model will predict the post-neoadjuvant chemotherapy efficacy and prognosis, offering assistance in personalized treatment decisions for gastric cancer patients.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age 18 years or older;

• Pathologically diagnosed with advanced gastric cancer in accordance with the American AJCC's TNM staging standards;

• Have not undergone any systematic anti-cancer treatments before neoadjuvant chemotherapy and have not had surgery for local progression or distant metastasis;

• Received standard neoadjuvant chemotherapy as recommended by the clinical guidelines, and have documented treatment details;

• CT imaging and biopsy pathology images strictly taken within one month prior to starting neoadjuvant treatment;

• Patients possess comprehensive preoperative clinical information and post-operative TRG grading.

Locations
Other Locations
China
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
NOT_YET_RECRUITING
Beijing
Peking Union Medical College Hospital
NOT_YET_RECRUITING
Beijing
Peking University Cancer Hospital & Institute
RECRUITING
Beijing
Peking University People's Hospital
NOT_YET_RECRUITING
Beijing
Xiangya Hospital of Central South University
NOT_YET_RECRUITING
Changsha
Fujian Cancer Hospital
NOT_YET_RECRUITING
Fuzhou
Fujian Medical University Union Hospital
RECRUITING
Fuzhou
Affiliated Cancer Hospital & Institute of Guangzhou Medical University
NOT_YET_RECRUITING
Guangzhou
First Affiliated Hospital, Sun Yat-Sen University
NOT_YET_RECRUITING
Guangzhou
Nanfang Hospital of Southern Medical University
NOT_YET_RECRUITING
Guangzhou
Sixth Affiliated Hospital, Sun Yat-sen University
RECRUITING
Guangzhou
Yunnan Cancer Hospital
RECRUITING
Kunming
Cancer Hospital of Guangxi Medical University
NOT_YET_RECRUITING
Nanning
The Affiliated Hospital of Qingdao University
NOT_YET_RECRUITING
Qingdao
Ruijin Hospital
NOT_YET_RECRUITING
Shanghai
First Hospital of China Medical University
NOT_YET_RECRUITING
Shenyang
The First Affiliated Hospital of Soochow University
NOT_YET_RECRUITING
Suzhou
Tianjin Medical University Cancer Institute and Hospital
NOT_YET_RECRUITING
Tianjin
Henan Cancer Hospital
RECRUITING
Zhengzhou
The First Affiliated Hospital of Zhengzhou University
RECRUITING
Zhengzhou
Zhenjiang First People's Hospital
RECRUITING
Zhenjiang
Italy
San Raffaele University Hospital, Italy
RECRUITING
Milan
Contact Information
Primary
Di Dong, Ph.D.
di.dong@ia.ac.cn
+86 13811833760
Time Frame
Start Date: 2023-09-10
Estimated Completion Date: 2029-12-31
Participants
Target number of participants: 200
Treatments
Gastric Cancer Patients Undergoing Neoadjuvant Chemotherapy
This group comprises participants diagnosed with advanced gastric cancer. The participants will be treated with standard neoadjuvant chemotherapy regimens recommended by clinical guidelines. Treatment details, including the generic name of the drugs, dosage form, dosage, frequency, and duration, will be recorded according to the specific regimen.
Related Therapeutic Areas
Sponsors
Collaborators: Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Cancer Hospital of Guangxi Medical University, Peking Union Medical College Hospital, Ruijin Hospital, Yunnan Cancer Hospital, Henan Cancer Hospital, Peking University Cancer Hospital & Institute, The Affiliated Hospital of Qingdao University, First Affiliated Hospital, Sun Yat-Sen University, First Hospital of China Medical University, Xiangya Hospital of Central South University, Peking University People's Hospital, The First Affiliated Hospital of Zhengzhou University, Nanfang Hospital, Southern Medical University, San Raffaele University Hospital, Italy, The First Affiliated Hospital of Soochow University, Fujian Medical University Union Hospital, Sixth Affiliated Hospital, Sun Yat-sen University, Fujian Cancer Hospital, Tianjin Medical University Cancer Institute and Hospital, Zhenjiang First People's Hospital, Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Leads: Chinese Academy of Sciences

This content was sourced from clinicaltrials.gov